平安! 发表于 2011-11-9 19:57
9 G, U( w8 w; pPazopanib (100 mg/kg/day free base equivalent) : }. E1 K( ^/ v; [
这是个已经在美国上市的老药了,能下载到正式药物使用说明书英文版。
, _ i7 M$ o/ C* o) ~搜索了一下,原料一大堆。8 T" c' Z+ H% I' {, b& v. I }
2 ^( t2 \; A, [- O对不起!100mg/kg是用于移植瘤的,我弄错了。& L" b# O2 C+ R6 D
' e c: B1 x& v, o l1 {+ E# L+ d以下是正版说明书的推荐用量。3 a$ L; N1 u( d' b; n; C' h
9 l0 T$ ], E( k- m+ J( W% u) S--------------------- DOSAGE AND ADMINISTRATION ----------------
3 U" c r& j5 m9 f2 {* 800 mg orally once daily without food (at least 1 hour before or 2 hours after a meal). (2.1)
% l1 X/ j2 b! a3 m5 p( T; s* Baseline moderate hepatic impairment – 200 mg orally once daily. Not recommended in patients with severe hepatic impairment. (2.2)
: U$ v2 q9 {( P( u6 p---------------------DOSAGE FORMS AND STRENGTHS --------------$ D5 } |" I1 v4 W+ c. E
200 mg tablets. (3)
, _3 g4 I6 _: S9 e+ Y2 e" ]-------------------------------CONTRAINDICATIONS------------------------ |